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Thermodynamic Stability of Wild-Type and Mutant p53 Core Domain

โœ Scribed by Alex N. Bullock, Julia Henckel, Brian S. DeDecker, Christopher M. Johnson, Penka V. Nikolova, Mark R. Proctor, David P. Lane and Alan R. Fersht


Book ID
123640971
Publisher
National Academy of Sciences
Year
1997
Tongue
English
Weight
1011 KB
Volume
94
Category
Article
ISSN
0027-8424

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Cytotoxic T lymphocytes (CTL) recognize peptides presented at the cell surface in association with major histocompatibility complex (MHC) class I molecules. The finding that peptides binding to MHC class I molecules share common amino acid motifs renders feasible the selection of antigenic peptides