Thermal rearrangement of allyl substituted 2H-azirines to 3-azabicyclo[3.1.0]hex-2-enes
โ Scribed by Padwa, Albert.; Carlsen, Per H. J.
- Book ID
- 126310141
- Publisher
- American Chemical Society
- Year
- 1976
- Tongue
- English
- Weight
- 315 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
The triplet sensitized irradiation of 3-allyl-diaryl-substituted cyclopropenes to m.l.O]hex-2-enes proceeds via an intramolecular [2+2]-cycloaddition followed by a subsequent rearrangement of the initially formed tricycl0[2.2.0.0~~~]hexane skeleton. Previous work from this laboratory has shown that
Azabicyclic systems have been extensively used in recent years as key structural components of various pharmaceutical agents. Consequently, flexible methods for the construction of azabicycles are of considerable interest. We have recently described a very general method for the construction of trop