Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides
✍ Scribed by Rogachev, Victor O; Metz, Peter
- Book ID
- 109946028
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 442 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1750-2799
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📜 SIMILAR VOLUMES
Enantiomerically pure dand g-sultams have been prepared by intramolecular [4+2] cycloaddition of N-1-phenylethyl substituted vinylsulfonamides with purely thermal activation and under high pressure. An optimized procedure for reductive debenzylation of the resultant d-sultams is also reported.
## Abstract For Abstract see ChemInform Abstract in Full Text.
A variety of substituted furans a-6J undergo the intramolecular Die&Alder reaction at high pressure (12.5 kbar) to provide oxatricyclo adducts Q-12) within 24 hours at room temperature.