Therapy-related T cell lymphoblastic lymphoma with t(11;19)(q23;p13) and MLL gene rearrangement
β Scribed by Thandla, S; Alashari, M; Green, DM; Aplan, PD
- Book ID
- 110054342
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 95 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0887-6924
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## Abstract Thirteen cosmid probes were mapped on the long arm of chromosome 11 between 11q22 and 11q24 by nonradioactive in situ hybridization. Starting with these localizations and those of other probes mapped to 11q23, four acute leukemias with translocations involving 11q23 were studied with th
CBP, which is located on 16p13 and encodes a transcriptional adaptor/coactivator protein, has been shown to fuse by the t(8;16)(p11;p13) translocation to MOZ on 8p11 in acute myeloid leukemia. We found a t(11;16)(q23;p13) in a child with therapy-related chronic myelomonocytic leukemia. Subsequent re