Therapy of refractory/relapsed acute myeloid leukemia and blast crisis of chronic myeloid leukemia with the combination of cytosine arabinoside, tetrahydrouridine, and carboplatin
β Scribed by Jonathan H. Marsh; Willi Kreis; Barbara Barile; Silvia Akerman; Philip Schulman; Steven L. Allen; Linda C. DeMarco; Michael W. Schuster; Daniel R. Budman
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 428 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0344-5704
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## Background: The objectives of the study were to evaluate the antileukemic efficacy and toxicity profiles of the combination of fludarabine and intermediate-dose cytosine arabinoside (ara-c) in refractory or relapsed adult acute lymphocytic leukemia (all). patients and methods. thirty adults with
Treatment of the myeloid blast phase of chronic granulocytic leukemia is still a major problem in clinical hematology. Alternate-day plicamycin and hydroxyurea treatment was reported to induce remissions in the majority of patients with myeloid blast phase by Koller and Miller in 1986 Subsequently w