Results of conventional-dose cytosine arabinoside and idarubicin in elderly patients with acute myeloid leukemia
✍ Scribed by A. Heyll; C. Aul; F. Gogolin; V. Runde; D. Söhngen; G. Meckenstock; H. -H. Wolf; J. Zahner; M. Burk; M. Winkelmann; W. Schneider
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 549 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0939-5555
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## BACKGROUND Drug resistance and early disease recurrence were major contributing factors in the limited survival of patients with acute lymphocytic leukemia (ALL). New chemotherapeutic agents and drug combinations were employed in refractory patients to overcome drug resistance. ##
## BACKGROUND. Peripheral nerve toxicity has been reported but is not a commonly recognized complication of high dose cytosine arabinoside (HDAC) therapy. This study was undertaken to estimate the prevalence and describe the clinical spectrum of acute polyneuropathy associated with HDAC therapy fo
Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours