Therapeutic studies in NZB/NZW mice.
β Scribed by Alfred D. Steinberg; Randall Krakauer; James L. Reinertsen; Lynell W. Klassen; David Ilfeld; J. Patton Reeves; Gary W. Williams; Tatiana Antonovych
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 498 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
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## Abstract NZB/NZW F~1~ female mice received levamisole in an attempt to increase suppressor T cell function. Responses varied with dosage of drug and age of mice. When treatment with 25 ΞΌg/gm doses (intermittent or daily) was begun at 12 weeks of age, nephritis was accelerated in spite of transie
## Abstract Prepubertal castration of female NZB/NZW (B/W) hybrid mice did not influence mortality, whereas prepubertal castration of male B/W mice caused premature death and enhanced autoantibody formation. Prepubertal castration combined with the administration of sustained estradiolβ17βΞ² (Eβ2) e