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Therapeutic doses of acetaminophen stimulate the turnover of cysteine and glutathione in man

โœ Scribed by Lauterburg, Bernhard H.; Mitchell, Jerry R.

Book ID
122348817
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
425 KB
Volume
4
Category
Article
ISSN
0168-8278

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Toxic Doses of Acetaminophen Suppress He
Toxic Doses of Acetaminophen Suppress Hepatic Glutathione Synthesis in Rats
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The effect of a toxic dose of acetaminophen on hepatic glutathione turnover was studied in fed and fasted rats. Following the administration of 1 g m per kg of acetaminophen, the fractional rate of glutathione turnover increased from 0.19 to 0.28 hr-' in fed rats and from 0.43 to 0.50 hr-' in rats f

Quantitative determination of the glutat
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