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Theoretical Study on the Inhibition of Ribonucleotide Reductase by 2‘-Mercapto-2‘-deoxyribonucleoside-5‘-diphosphates

✍ Scribed by Pereira, Susana; Fernandes, Pedro Alexandrino; Ramos, Maria João


Book ID
126200886
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
293 KB
Volume
127
Category
Article
ISSN
0002-7863

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Theoretical study of ribonucleotide redu
✍ Susana Pereira; Pedro Alexandrino Fernandes; Maria João Ramos 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 414 KB

## Abstract 2′‐Azido‐2′‐deoxyribonucleoside 5′‐diphosphates are mechanism‐based inhibitors of Ribonucleotide Reductase. Considerable effort has been made to elucidate their mechanism of inhibition, which is still controversial and not fully understood. Previous studies have detected the formation o