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TheBCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia

✍ Scribed by Künkele, Annette; Grosse-Lordemann, Anja; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes H; Bachmann, Hagen S

Book ID
121618103
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
191 KB
Volume
13
Category
Article
ISSN
1471-2407

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Regulatory BCL2 promoter polymorphism (−
Regulatory BCL2 promoter polymorphism (−938C>A) is associated with adverse outcome in patients with prostate carcinoma
✍ Hagen S. Bachmann; Lukas C. Heukamp; Klaus J. Schmitz; Caroline F. Hilburn; Phil 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract Molecular markers predictive of prostate cancer prognosis are urgently needed. Overexpression of the antiapoptotic protein, Bcl‐2, has repeatedly been shown to be associated with adverse outcome in this malignancy. We hypothesized that a regulatory __BCL2__ −938C>A promoter polymorphism