Individualized methotrexate dosing in children with relapsed acute lymphoblastic leukemia
โ Scribed by Wall, A M; Gajjar, A; Link, A; Mahmoud, H; Pui, C-H; Relling, M V
- Book ID
- 110054456
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 104 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0887-6924
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๐ SIMILAR VOLUMES
The relationship between salivary methotrexate (MTX) concentration and severity of oral mucositis after administration of MTX was investigated in six children with acute lymphoblastic leukemia. They received two administrations of MTX at 500 mgm' with one third given bolusly and the remainder by 24-
Six hundred thirty-four children with acute lymphoblastic leukemia (ALL) were randomized to receive sanctuary therapy consisting of either cranial irradiation (CRT) plus intrathecal (IT) methotrexate (MTX) or three courses of intermediate-dose methotrexate (IDM) plus intrathecal methotrexate. Two hu
## Abstract In a retrospective review which covered the whole Dutch childhood population of approximately 3 million children we studied the prognosis in 164 children with acute lymphoblastic leukemia (ALL) who were initially treated between 1973 and 1983, and who had an isolated bone marrow relapse