Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome
β Scribed by Robinson, H M; Broadfield, Z J; Cheung, K L; Harewood, L; Harris, R L; Jalali, G R; Martineau, M; Moorman, A V; Taylor, K E; Richards, S
- Book ID
- 110055670
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 78 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0887-6924
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## Abstract We report a case of childhood acute lymphoblastic leukemia (ALL) with both acute myeloid leukemia 1 (__AML1__) amplification and 17q25 deletion. __AML1__ gene is located on 21q22 and encodes a transcription factor. __AML1__ amplification is a common finding in childhood ALL, and itis ob