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The αvβ3 Integrin, NF-κB, Osteoprotegerin Endothelial Cell Survival Pathway: Potential Role in Angiogenesis

✍ Scribed by Marta Scatena; Cecilia Giachelli

Book ID
114342024
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
517 KB
Volume
12
Category
Article
ISSN
1050-1738

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## Abstract Tumor malignancy is associated with several features such as proliferation ability and frequency of metastasis. Osteopontin (OPN), which abundantly expressed in bone matrix, is involved in cell adhesion, migration, invasion and proliferation via interaction with its receptor, that is, α