THE α-ALKYLATION OF ENOLATES FROM THE LITHIUM-AMMONIA REDUCTION OF α,β-UNSATURATED KETONES
✍ Scribed by Stork, Gilbert; Rosen, Perry; Goldman, Norman L.
- Book ID
- 126874690
- Publisher
- American Chemical Society
- Year
- 1961
- Tongue
- English
- Weight
- 252 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
## Abstract Eleven structurally different α, β‐unsaturated ketones were subjected to the __Clemmensen__ reduction under anhydrous conditions using amalgamated zinc, hydrogen chloride in a solution of ethyl ether, and acetic anhydride. In all cases but one the formation of cyclopropyl acetates was o
Y-alkylation of the title compounds with primary alkyl iodides is possible only when both a'-protons are first ionized with excess lithium diisoproylamide. a) M. Cooke and R. Goswami, J. Am. Chem. c, \_, 99 642 (1977). --b) J. A. M. van den Goorbergh and A. van der Cen, Rec. Trav. Chim., 102, 393 (