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The X-ray crystal structures of loxapine {2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine} and amoxapine {2-chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine}

✍ Scribed by Cosulich, D. B. ;Lovell, F. M.


Book ID
114524089
Publisher
International Union of Crystallography
Year
1977
Weight
780 KB
Volume
33
Category
Article
ISSN
0567-7408

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The synthesis and chemistry of [11-14C]-
✍ J. M. Harrison; T. D. Inch; D. G. Upshall πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 French βš– 211 KB

## Abstract The synthesis of [11‐^14^C]‐dibenz[b,f][1,4]oxazepine 1 is described. Chromium trioxide – pyridine oxidation of 1 gives [11‐^14^C]‐10, 11‐dihydrodibenz [b,f][1,4] oxazepin‐11‐one 3 which on hydrolysis gives 2‐amino‐2′‐[^14^C]‐carboxydiphenylether 4. Hydrogenation of 1 affords [11‐^14^C]