𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis and chemistry of [11-14C]-dibenz[b,f] [1,4]oxazepine

✍ Scribed by J. M. Harrison; T. D. Inch; D. G. Upshall

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
211 KB
Volume
14
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The synthesis of [11‐^14^C]‐dibenz[b,f][1,4]oxazepine 1 is described. Chromium trioxide – pyridine oxidation of 1 gives [11‐^14^C]‐10, 11‐dihydrodibenz [b,f][1,4] oxazepin‐11‐one 3 which on hydrolysis gives 2‐amino‐2′‐[^14^C]‐carboxydiphenylether 4. Hydrogenation of 1 affords [11‐^14^C]‐10, 11‐dihydrodibenz[b,f][1,4]oxazepine 5. The enzymic conversion of 1 into 2‐amino‐2′‐[^14^C]‐hydroxymethyldiphenyl ether 6 is described.

📜 SIMILAR VOLUMES

Improved etherification procedure for th
Improved etherification procedure for the preparation of dibenz[b,f][1,4]oxazepine
✍ H. Fakhraian; Y. Nafary; A. Yarahmadi; H. Hadj-Ghanbary 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 200 KB

## Abstract magnified image The effect of temperature and catalyst on the yield and rate of the etherification reaction between **1** and **2** was investigated and alternative methods for separation of **3** and **4** from the reaction mixture have been described.

Reinvestigation of alternative method fo
Reinvestigation of alternative method for the preparation of dibenz[b,f][1,4]oxazepine
✍ Hossein Fakhraian; Yaser Nafary 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 86 KB 👁 1 views

## Abstract magnified image Two distinct alternative methods using different starting materials for the preparation of dibenz[__b__,__f__][1, 4]oxazepine (**7**, CR) were reinvestigated. The possibility of __trans‐cis__ conversion of the Schiff base **5cis**, **5trans** (produced from **1** and **