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The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells

✍ Scribed by Yoji Murata; Tetsuhiro Kudoh; Haruo Sugiyama; Kumao Toyoshima; Tetsu Akiyama


Book ID
117107611
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
529 KB
Volume
409
Category
Article
ISSN
0014-5793

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The expression of the Wilms tumor suppressor gene WT1 is largely restricted to elements of the developing urogenital system. In the fetal kidney, WT1 transcripts are present at low levels in the condensing mesenchyme and at much higher levels in differentiating glomerular epithelium and are not dete