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Suppression of Wilms' tumor gene (WT1) expression induces G2M arrest in leukemic cells

✍ Scribed by Tamotsu Yamagami; Hiroyasu Ogawa; Hiroya Tamaki; Yusuke Oji; Toshihiro Soma; Yoshihiro Oka; Toyoshi Tatekawa; Akihiro Tsuboi; Eui Ho Kim; Tetsu Akiyama; Haruo Sugiyama


Book ID
114119181
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
213 KB
Volume
22
Category
Article
ISSN
0145-2126

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The expression of the Wilms tumor suppressor gene WT1 is largely restricted to elements of the developing urogenital system. In the fetal kidney, WT1 transcripts are present at low levels in the condensing mesenchyme and at much higher levels in differentiating glomerular epithelium and are not dete