The von Hippel-Lindau (VHL) disease tumor-suppressor gene is not mutated in nasopharyngeal carcinomas
β Scribed by Yi Sun; Allan Hildesheim; Hua Li; Anne P. Lanier; Ya Cao; Kai-Tai Yao; Czau-Siung Yang; Nancy H. Colburn
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- French
- Weight
- 231 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0020-7136
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Communicated by Victor A. McKusick von Hippel-Lindau disease (VHL) is an inherited neoplastic disorder characterized by the development of tumors in the eyes, brain, spinal cord, inner ear, adrenal gland, pancreas, kidney, and epididymis. The VHL tumor suppressor gene was identified in 1993. Initial
## Communicated by Lap-Chee Tsui Von Hippel-Lindau (VHL) disease is a dominantly inherited disorder predisposing those afflicted to hemangioblastomas of the central nervous system and the retina, renal cell carcinomas, pheochromocytomas, and pancreatic tumors. The disease has been associated with