𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas

✍ Scribed by Spiros Miyakis; George Sourvinos; Triantafyllos L. Liloglou; George P. Stathopoulos; John K. Field; Demetrios A. Spandidos


Publisher
John Wiley and Sons
Year
2000
Tongue
French
Weight
33 KB
Volume
88
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Germline mutation profile of the VHL gen
✍ Sylviane Olschwang; StΓ©phane Richard; CΓ©cile Boisson; Sophie Giraud; Pierre Laur πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 252 KB πŸ‘ 1 views

## Communicated by Lap-Chee Tsui Von Hippel-Lindau (VHL) disease is a dominantly inherited disorder predisposing those afflicted to hemangioblastomas of the central nervous system and the retina, renal cell carcinomas, pheochromocytomas, and pancreatic tumors. The disease has been associated with

Improved detection of germline mutations
✍ Catherine Stolle; Gladys Glenn; Berton Zbar; Jeffrey S. Humphrey; Peter Choyke; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 201 KB πŸ‘ 1 views

Communicated by Victor A. McKusick von Hippel-Lindau disease (VHL) is an inherited neoplastic disorder characterized by the development of tumors in the eyes, brain, spinal cord, inner ear, adrenal gland, pancreas, kidney, and epididymis. The VHL tumor suppressor gene was identified in 1993. Initial

Genomic organization and chromosomal loc
✍ Steven C. Clifford; Sally Walsh; Katie Hewson; Elaine K. Green; Astrid Brinke; P πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 134 KB πŸ‘ 2 views

Germline mutations in the von Hippel-Lindau (VHL) disease tumor suppressor gene (TSG) convey a high risk of clear-cell renal-cell carcinoma (CC-RCC) and most sporadic CC-RCCs demonstrate somatic inactivation of the VHL TSG. However, the existence of further CC-RCC gatekeeper genes is implied by CC-R