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The use of monoclonal antibodies in diagnostic tests for Becker and Duchenne muscular dystrophy

✍ Scribed by Ralf Gold; Wolfram Kreß; Heinz Reichmann; Clemens R. Müller


Publisher
Springer
Year
1993
Tongue
English
Weight
490 KB
Volume
240
Category
Article
ISSN
0340-5354

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## Communicated by Ulf Landegren Duchenne and Becker muscular dystrophy (DMD and BMD) are caused by mutations in the dystrophin gene. Large rearrangements in the gene are found in about two-thirds of DMD patients, with B60% carrying deletions and 5-10% carrying duplications. Most of the remaining