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Characterization of genetic deletions in becker muscular dystrophy using monoclonal antibodies against a deletion-prone region of dystrophin

✍ Scribed by Thanh, Le Thiet ;Man, Nguyen Thi ;Hori, S. ;Sewry, C. A. ;Dubowitz, V. ;Morris, G. E.


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
953 KB
Volume
58
Category
Article
ISSN
0148-7299

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Pattern of deletions of the dystrophin g
✍ Coral-Vázquez, Ramón; Arenas, Diego; Cisneros, Bulmaro; Peñaloza, Laura; Salaman 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 3 views

We have analyzed 59 unrelated Mexican Duchenne/Becker muscular dystrophy patients (DMD/BMD) using PCR analysis of the 2 prone deletion regions in the DMD gene. Thirty one (52%) of the patients had a deletion of one or several of the exons. Most of the alterations (87%) were clustered in exons 44-52,