More deletions in the 5′ region than in the central region of the dystrophin gene were identified among filipino duchenne and becker muscular dystrophy patients

Pattern of deletions of the dystrophin g

Pattern of deletions of the dystrophin gene in Mexican Duchenne/Becker muscular dystrophy patients: The use of new designed primers for the analysis of the major deletion “hot spot” region

✍ Coral-Vázquez, Ramón; Arenas, Diego; Cisneros, Bulmaro; Peñaloza, Laura; Salaman 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 2 views

We have analyzed 59 unrelated Mexican Duchenne/Becker muscular dystrophy patients (DMD/BMD) using PCR analysis of the 2 prone deletion regions in the DMD gene. Thirty one (52%) of the patients had a deletion of one or several of the exons. Most of the alterations (87%) were clustered in exons 44-52,