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The Use of Isotope Effects to Elucidate Enzyme Mechanisms

✍ Scribed by K. Barbara Schowen and Richard L. Schowen

Book ID
124447727
Publisher
University of California Press
Year
1981
Tongue
English
Weight
369 KB
Volume
31
Category
Article
ISSN
0006-3568

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πŸ“œ SIMILAR VOLUMES

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## Abstract Isotope effects are a powerful tool for determining the mechanisms of enzymatic reactions. Methods for measurement of isotope effects are reviewed and the equations that describe observed isotope effects and permit determination of intrinsic isotope effects on the isotope‐sensitive step

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## Abstract The basic principles and illustrative applications to enzyme mechanisms of solvent isotope effects, with emphasis on the use of rate measurements in mixtures of protium and deuterium oxides (β€˜proton inventories’), are reviewed over a period slightly shorter than the history of this Jour