✦ LIBER ✦

The use of immobilized glutamate dehydrogenase to synthesize 13N-labeled l-amino acids

✍ Scribed by Arthur J.L. Cooper; Alan S. Gelbard

Book ID: 102985678
Publisher: Elsevier Science
Year: 1981
Tongue: English
Weight: 597 KB
Volume: 111
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(81)90225-6

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✦ Synopsis

By utilizing glutamate dehydrogenase immobilized onto CNBr-activated Sepharose it is possible to synthesize six L-L3N-amino acids in high radiochemical yield (S-140 mCi) and in high (>99%) radiochemical purity. These '3N-amino acid solutions are potentially suitable for whole body and organ imaging in large animals and man.

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