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The use of bromodeoxyuridine labeling in the human lymphocyte HGPRT somatic mutation assay

✍ Scribed by Patricia Ostrosky-Wegman; M.Regina Montero; Cristina Cortinas de Nava; Raymond R. Tice; Richard Albertini

Book ID
113255048
Publisher
Elsevier Science
Year
1987
Weight
352 KB
Volume
191
Category
Article
ISSN
0165-7992

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The mutagenic potential of acrolein has been studied with a wide range of in vitro and in vivo genetic toxicity assays. The data often have been conflicting, especially with the Ames assay. This study was undertaken to assess the mutagenic potential of acrolein using the CHOlHGPRT assay, both with a