The proliferative potential of human ependymomas measured by in situ bromodeoxyuridine labeling
β Scribed by Tadashi Nagashima; Takao Hoshino; Kyung G. Cho; Michael S. B. Edwards; Roger J. Hudgins; Richard L. Davis
- Book ID
- 102671751
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 633 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0008-543X
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Fifky-seven patients with brain tumors (29 gliomas, 23 meningiomas, 5 miscellaneous) received infusions of intravenous iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) 1-5 hr apart shortly before tumor removal. Excised tumor specimens were stained sequentially for BUdR and IUdR. The percentage o
The prognostic significance of histopathological grade for postoperative outcome is not yet known for ependymomas. Data on proliferation kinetics of these tumors are few. In our study, the growth fraction was immunohistochemically determined by labelling cell nuclei with the monoclonal antibody Ki-6