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The Ubiquitin–Proteasome System in Retinal Health and Disease

✍ Scribed by Campello, Laura; Esteve-Rudd, Julián; Cuenca, Nicolás; Martín-Nieto, José


Book ID
120359380
Publisher
Springer
Year
2013
Tongue
English
Weight
616 KB
Volume
47
Category
Article
ISSN
0893-7648

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## Abstract Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin–proteasome system (UPS) to clear unwanted proteins, resulting in protein