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The ubiquitin proteasome system and efficacy of proteasome inhibitors in diseases

โœ Scribed by Selvarajan Chitra; Ganesan Nalini; Gopalakrishnan Rajasekhar


Book ID
114930922
Publisher
Wiley (Blackwell Publishing)
Year
2012
Tongue
English
Weight
299 KB
Volume
15
Category
Article
ISSN
1756-1841

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โœ Jayhyuk Myung; Kyung Bo Kim; Craig M. Crews ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 513 KB

## Abstract The ubiquitinโ€proteasome pathway has emerged as a central player in the regulation of several diverse cellular processes. Here, we describe the important components of this complex biochemical machinery as well as several important cellular substrates targeted by this pathway and exampl