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The tylosin-biosynthetic genes of Streptomyces fradiae

โœ Scribed by Eric Cundliffe; Neil Bate; Andrew Butler; Steven Fish; Atul Gandecha; Louise Merson-Davies

Book ID
110308921
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
279 KB
Volume
79
Category
Article
ISSN
0003-6072

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Cloning and expression of a tylosin resi
Cloning and expression of a tylosin resistance gene from a tylosin-producing strain of Streptomyces fradiae
โœ Birmingham, Virginia A. ;Cox, Karen L. ;Larson, Jeffrey L. ;Fishman, Scott E. ;H ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 919 KB

A gene conferring high-level resistance to tylosin in Streptomyces lividans and Streptomyces griseofuscus was cloned from a tylosin-producing strain of Streptomyces fradiae. The tylosin-resistance (Tylr) gene (tlrA) was isolated on five overlapping DNA fragments which contained a common 2.6 Kb KpnI