𝔖 Bobbio Scriptorium
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The tRNA cycle and its relation to the rate of protein synthesis

✍ Scribed by H. Liljenström; G. Heijne; C. Blomberg; J. Johansson

Book ID
104688528
Publisher
Springer
Year
1985
Tongue
English
Weight
435 KB
Volume
12
Category
Article
ISSN
1432-1017

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✦ Synopsis

With the aid of a kinetic model, we have investigated how the adaptation between the various components of the tRNA cycle and the codon frequencies affects the rate of protein synthesis. Depending on the relative amounts of total tRNA, synthetase and ribosomes, the optimal correlations vary between a situation where all tRNA species are either present in equal amounts or are present in amounts proportional to the square-root of the corresponding codon frequencies, and a situation where the amounts of the different tRNA species present are linearly proportional to the codon frequencies.

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