β Scribed by R. C. A. Henderson; B. S. Cox; R. Tubb
No coin nor oath required. For personal study only.
Several strains of yeast used in the brewing industry have been transformed using a plasmid carrying the dominant gene for copper resistance, CUP1. This technique will make it possible to consider genetic improvement of commercially useful yeasts through the introduction of desirable genes one at a time without disturbing the other characteristics of the strain. Selection for copper resistance may make it possible to regulate plasmid copy-number and stability.
π SIMILAR VOLUMES
A cadmium-resistant strain of Saccharomyces cerevisiae produces a cadmium metallothionein with the same characteristics as the copper metallothionein that is encoded by CUP 1 in a copper-resistant strain. The structural gene for metallothionein from the cadmium-resistant strain resembles CUP1 in ter
Mter a short introduction on the historical background of the development of Saccharomyces cere&iae as a model eukaryote, a review is given on the present state of genetics and molecular biology of copper resistance in 5. cereviaiae. The gene CUPl encodes a protein (copper metallothionein) of a mole