𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The TP53 signaling network in mammals and worms

✍ Scribed by Jolliffe, A. K.; Derry, W. B.

Book ID
118733997
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
278 KB
Volume
12
Category
Article
ISSN
2041-2649

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Impact of mutant p53 functional properti
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
✍ Audrey Petitjean; Ewy Mathe; Shunsuke Kato; Chikashi Ishioka; Sean V. Tavtigian; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

The tumor suppressor gene TP53 is frequently mutated in human cancers. More than 75% of all mutations are missense substitutions that have been extensively analyzed in various yeast and human cell assays. The International Agency for Research on Cancer (IARC) TP53 database (www-p53.iarc.fr) compiles

Common polymorphisms in TP53 and MDM2 an
Common polymorphisms in TP53 and MDM2 and the relationship to TP53 mutations and clinical outcomes in women with ovarian and peritoneal carcinomas
✍ Vijaya Galic; Julia Willner; Melissa Wollan; Ruchi Garg; Rochelle Garcia; Barbar πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 202 KB

## Abstract The importance of somatic __TP53__ mutations and germline __TP53__ codon 72 genotype in the survival of women with epithelial ovarian cancer is controversial. Recent data suggest that a promoter polymorphism in the __MDM2__ gene may influence age of cancer onset in a gender‐specific fas