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Focus on the p53 gene and cancer: Advances in TP53 mutation research

✍ Scribed by Thierry Soussi


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
70 KB
Volume
21
Category
Article
ISSN
1059-7794

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The tumor suppressor gene TP53 is frequently mutated in human cancers. More than 75% of all mutations are missense substitutions that have been extensively analyzed in various yeast and human cell assays. The International Agency for Research on Cancer (IARC) TP53 database (www-p53.iarc.fr) compiles

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