ChemInform Abstract: Stereocontrolled To
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Yoshihisa Kobayashi; Teppei Fujimoto; Tohru Fukuyama
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Article
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2010
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John Wiley and Sons
⚖ 26 KB
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Stereocontrolled Total Synthesis of (+)-K252a. -The cycloglycosidic indolocarbazole alkaloid (I) shows strong PKC inhibitory activity. A linear 23-step sequence starting from indole-3-acetic acid is developed for the synthesis of (I) in 10% overall yield. The known deoxyfuranose derivative (II) is u