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The synthesis of two repeating units of haemophilus influenzae type a capsular antigen

✍ Scribed by Barbara Grzeszczyk; Anna Banaszek; Aleksander Zamojski

Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 805 KB
Volume: 175
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(88)84144-2

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✦ Synopsis

The repeating units 2-O-beta-D-glucopyranosyl-L-ribitol 4'- and 1-phosphate of Haemophilus influenzae type a capsular antigen have been synthesised by condensation of an alpha-D-glucopyranosyl bromide derivative with 5-O-allyl-1,2,3-tri-O-benzyl-D-ribitol followed by selective deprotection of HO-4' or HO-1, phosphorylation, and removal of the blocking groups.

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