๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of fragments of the capsular polysaccharide of haemophilus influenzae type B, comprising two or three repeating units

โœ Scribed by P. Hoogerhout; D. Evenberg; C.A.A. van Boeckel; J.T. Poolman; E.C. Beuvery; G.A. van der Marel; J.H. van Boom

Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
292 KB
Volume
28
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The synthesis of the ribosyl-ribitol derivatives 12 and 1,7 (Scheme 2) is presented. The compounds served as building blocks for the preparation of protected fragments(2_4, n=l or 2; Fig. 2) of the title polysaccharide.

The bifunctional reagent bi.sCl-benzotriazolyll-Zchlorophenylphosphate (l_S, Fig. 2) was used for all phosphorylation reactions. Attachment to a spacer and complete deprotection of the products, to afford 2_5 (n=2 or 3), is described.

ACKNOWLEDGEMENTS.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of fragments of the capsular p
Synthesis of fragments of the capsular polysaccharide of haemophilus influenzae type B
โœ Zhi Yuan Wang; George Just ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 227 KB

The synthesis of fragments, comprising two and four repeating units, of the title polysaccharide Is described. A recent report' describing the synthesis of the Me compounds prompts us to disclose our own work, which differs in some aspects from the synthesis published by Hoogerhout et a/'. In our

The synthesis of two repeating units of
The synthesis of two repeating units of haemophilus influenzae type a capsular antigen
โœ Barbara Grzeszczyk; Anna Banaszek; Aleksander Zamojski ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 805 KB

The repeating units 2-O-beta-D-glucopyranosyl-L-ribitol 4'- and 1-phosphate of Haemophilus influenzae type a capsular antigen have been synthesised by condensation of an alpha-D-glucopyranosyl bromide derivative with 5-O-allyl-1,2,3-tri-O-benzyl-D-ribitol followed by selective deprotection of HO-4'

A new approach to the synthesis of a dim
A new approach to the synthesis of a dimeric fragment of the capsular polysaccharide of haemophilus influenzae type b
โœ Laval Chan; George Just ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 223 KB

The synthesis of the monomeric fragment of the Haemophilus injluettzae type b (HIb) polysaccharide starting from orthoacetate I. is described. The construction of the dimer is also reported. The poly-(ribosyl-ribitol-phosphate) (PRP) 1. capsular polysaccharide isolated from the Haemophilus inj7uenza