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Synthesis of p-trifluoroacetamidophenyl β-d-glucopyranoside 4-(d-ribit-5-yl phosphate) corresponding to the Haemophilus influenzae type a capsular antigen

✍ Scribed by Björn Classon; Per J. Garegg; Ingvar Lindh


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
360 KB
Volume
179
Category
Article
ISSN
0008-6215

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✦ Synopsis


The synthesis is described of the title glycoside which corresponds to the Haemophilus influenzae type a capsular antigen. The hydrogenphosphonate method was used with 3,3'-(chlorophosphonylidene)bis(2-oxo-1,3-oxazolidene) as the condensing agent.


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✍ Björn Classon; Per J. Garegg; Stefan Oscarson; Anna-Karin Tidén 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 809 KB

The synthesis is described of p-nitrophenyl 2-acetamido-3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta -D- mannopyranosiduronic acid, corresponding to the disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type d, which, after conversion of the p-nitro