✦ LIBER ✦

The synthesis of tritium-labelled azidothymidine

✍ Scribed by Sunil K. Aggarwal; David R. Shalinsky; Krishna C. Agrawal

Publisher: John Wiley and Sons
Year: 1988
Tongue: French
Weight: 209 KB
Volume: 25
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580251002

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✦ Synopsis

The synt esis of 3H-labelled azidothymidine (AZT) from accomplished by column chromatography. The purity of the labelled compound was determined by high performance 1 iquid chromatography connected with a radioactive flow detector. The labelled AZT was found to be stable at pH ranging from 2.3 to 7.4 at 37OC and at hyperthermic temperature o f 42OC.

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