Synthesis of 11C-labeled (ยฑ)-5-methyl-10
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Dale O. Kiesewetter; Ronald D. Finn; Kenner C. Rice; James A. Monn
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Article
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1990
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Elsevier Science
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The synthesis of C5 labeled (+-)-5-[11C]methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten- 5,10-imine [(+-)-[11C]MK801] has been accomplished via alkylation of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine-N-t- butylformamidine [(+-)-5-des-methyl MK801 formamidine). The 11C labeling is ac