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THE SYNTHESIS OF SOME NEW PHENYLURETHANS AS POTENTIAL LOCAL ANESTHETICS

โœ Scribed by HUTTON, KENNETH.


Book ID
125942952
Publisher
American Chemical Society
Year
1955
Tongue
English
Weight
548 KB
Volume
20
Category
Article
ISSN
0022-3263

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Synthesis of tritium labelled ropivacain
โœ Lars Gawell ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 290 KB ๐Ÿ‘ 1 views

A potential local anaesthetic, ropivacaine, is synthesized labelled with tritium. The label is introduced by reduction of a racemic tetrahydropyridine derivative with tritium gas. Resolution into the labelled enantiomers is accomplished by preferential crystallization with added carrier. 3H NMR.