Synthesis of alkylaminoalkylamides of substituted 2-aminopyrroles as potential local anesthetic and antiarrhythmic agents β-amines
✍ Scribed by J. Walter Sowell Sr; Alan J. Block; Mary Elizabeth Derrick; John J. Freeman; Joseph W. Kosh; Philip F. Mubarak; Paul A. Tenthorey
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 551 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Synthesis and Biological Evaluation of New Cyclopenteno[b]thiophene Derivatives as Local Anesthetic and Antiarrhythmic Agents. -A series of new 2-aminocyclopentenothiophene-3-carboxylates such as (V) and (VI) (12 examples in all) are synthesized as carticaine analogues. Compounds (Va), (Vc), (Vd), (
The aliphatic amines. 2-methyl-and 2-isopropyl-substituted 6-hydroxy-1-hexylamines were synthesized from ethyl-6-hydroxyhexanoate in 22% and 11% overall chemical yield respectively. 6-hydroxy-1 -hexylamine was available commercially. 6-hydroxy -l -hexylamine and its 2-methyl-and 2-isopropyl-substitu
A series of thiazolyl-N-substituted amides were synthesized and tested for anti-inflammatory activity. Their R M values were determined as an expression of their lipophilicity. Theoretical calculation of their lipophilicity, as clog P and log D 7.4 was also performed. The effect of the synthesized c
## Abstract A series of novel 4__β__‐[(4‐substituted)‐1,2,3‐triazol‐1‐yl]podophyllotoxin derivatives were synthesized by employing Cu^I^‐catalyzed click chemistry and evaluated for their anticancer activity against a panel of seven human cancer cell lines (HT‐29, HCT‐15, 502713, HOP‐62, A‐549, MCF‐