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Synthesis of tritium labelled ropivacaine — A new potential local anesthetic

✍ Scribed by Lars Gawell

Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
290 KB
Volume
24
Category
Article
ISSN
0022-2135

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✦ Synopsis

A potential local anaesthetic, ropivacaine, is synthesized labelled with tritium. The label is introduced by reduction of a racemic tetrahydropyridine derivative with tritium gas. Resolution into the labelled enantiomers is accomplished by preferential crystallization with added carrier. 3H NMR.

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