The reaction of terminal acetylenic ketones with NaI or LiBr gave almost exclusively E-B-iodo-or E-8-bromovinyl ketones in trifluoroacetic acid, while Z-Biodo-or Z-B-bromovinyl ketones were the major products in acetic acid. Trimethylsilyl iodide and oromide reacted smoothly with acetylenic ketones
The synthesis of secosteroid acetylenic ketones
โ Scribed by Masato Tanabe; David F. Crowe; Robert L. Dehn; George Detre
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- French
- Weight
- 191 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Acerylenic sityl ketone 1 undergoes smooth Michael addition reaction with different silylated nucleophiles to afford P=functionalized propenoylsitanes.
The structures 9 and 8 are proposed for the single isolated irradiation product of 5-oxo-5,10-secocholest-I( 10)en-3cc -yl acetate (6) [2] and for the minor product of irradiation of 5-oxo-5,10-secocholest-l(l0)-en-3~ -yl acetate (1) [3], respectively. These compounds are formed in an alternative re
Dedicated to Professor Kurt Schaffner on the occasion of his 60th birthday (12.VIII. 91) UV irradiation of the unsaturated (E)-S,lO-secosteroidal ketones 1 and 6 results, in addition to (E/Z)-isomerization, in an intramolecular Paterno-Biichi reaction and, in the case of 1, in transannular cyclizati