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Efficient methods for the preparation of acetylenic ketones

✍ Scribed by H.D. Verkruijsse; Y.A. Heus-Kloos; L. Brandsma


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
372 KB
Volume
338
Category
Article
ISSN
0022-328X

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It has been about 25 years since Staab prepared a hexameric phenyl-ethynyl macrocycle by the statistical cyclization of the copper salt of m-iodo-phenylacetylene in 4.6% yield. Since that time, different methodologies have been investigated that allow not only the preparation of selec-tively functio