Reactivity of acetylenic silyl ketones: synthesis of functionalized propenoylsilanes
โ Scribed by Alessandro Degl'Innocenti; Antonella Capperucci; Gianna Reginato; Alessandro Mordini; Alfredo Ricci
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 168 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Acerylenic sityl ketone 1 undergoes smooth Michael addition reaction with different silylated nucleophiles to afford P=functionalized propenoylsitanes.
๐ SIMILAR VOLUMES
Allenoxyborinates, easily generated via the 1,4-addition of dicyclohexylborane to a,~acetylenic ketones, react in situ with excess starting ketone to afford stereodefined, functionalized trisubstituted olefins in high yields.
The Reaction of ฮฑ,ฮฒ-Acetylenic Ketones with Dicyclohexylborane: Stereoselective Synthesis of Functionalized Trisubstituted Olefins. -ฮฑ,ฮฒ-Acetylenic ketones (I) (6 compounds) undergo 1,4-addition of dicyclohexylborane to give allenoxyborinate intermediates which react with excess starting ketone to
## Abstract The orgnaometal reagents, generated in situ, are stable at room temperature and react smoothly with a broad spectrum of carboxylic acid chlorides.