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The synthesis of [ring-U-14C] DDD from [ring-U-14C] DDT using rat liver homogenate

✍ Scribed by S. C. Fawcett; L. J. King; P. I. Stanley; P. J. Bunyan


Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
164 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

1,1‐Di[ring‐U‐^14^C] (4‐chlorophenyl)‐2,2‐dichloroethane ([^14^C] DDD) was prepared by the anaerobic incubation of 1,1‐di[ring‐U‐^14^C] (4‐chlorophenyl)‐2,2,2‐trichloroethane ([^14^C] DDT) with homogenised rat liver in buffer. This gave a good yield of DDD which was purified chromatographically. The overall recovery of 99.5% pure DDD was 68%.


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