𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis of oligodeoxynucleotides containing 4-thiothymidine residues

✍ Scribed by Theo T. Nikiforov; Bernard A. Cornolly


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
282 KB
Volume
32
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


Olgodeoqnucleotides contarnug 4-thothymzdm residues were obtauwdusing the ph~?sphoramtdttes of 2 and J Treatment with CHJOSK tn EtOH was used to rntroduce the I-throketo $mctron at the olqodeoqnucleotrde level.

Recently, we have reported the synthesis of 5'-0-(4,4'-dimethoxytrity1)-4-throcyanatothymidine


πŸ“œ SIMILAR VOLUMES


Solid-phase synthesis of oligodeoxynucle
✍ H. C. P. F. Roelen; H. F. Brugghe; H. van den Elst; G. A. van der Marel; J. H. v πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 647 KB

## Abstract Immobilized and fully protected oligodeoxynucleotides containing a 4‐(1,2,4‐triazolyl)‐thymidine residue at a predetermined position were prepared according to a well‐established phosphite triester methodology using 2‐cyanoethyl phosphoramidites of a 4‐(1,2,4‐triazolyl)‐substituted thym

Solid phase synthesis of oligonucleotide
✍ Richard Cosstick; Joseph S. Vyle πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 254 KB

Summarv-A 5'-O-monomethoxytritylthymidine-3'-S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3'-thiothymidine on a solid phase support. The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate. Polynucleotide analogues conta