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The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment

✍ Scribed by M. M. Smith; P. Ghosh

Publisher
Springer
Year
1987
Tongue
English
Weight
996 KB
Volume
7
Category
Article
ISSN
0172-8172

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## Abstract Cells of a newly established rat fibroblast line (SEN) in culture synthesize mucopolysaccharides, which have been identified as hyaluronic acid, chondroitin‐4‐sulfate and heparan sulfate. Treatment of the cells with adenosine 3β€²:5′‐cyclic monophosphate resulted in a marked stimulation o