𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The synthesis of dihematoporphyrin ether and related porphyrin dimers

✍ Scribed by Ian K Morris; A.David Ward

Book ID
104221328
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
246 KB
Volume
29
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

f&M.

Dihematoporphyrin ether (DHE) has been synthesised by two separate procedures; these routes also allow the synthesis of ether linked porphyrin dimers containing one or two vinyl groups rather than hydroxyethyl side chains. The latter dimers, but not DHE, have anti-cancer activity.

Hematoporphyrin derivative (HPD) is a complex mixture of porphyrins that is of considerable interest as a new anti-cancer agent.' HPD is administered intravenously and selectively localizes in tumour tissue. Activation of these porphyrins by a 629 nm light

πŸ“œ SIMILAR VOLUMES

Synthesis of triazole- and pyridine-brid
Synthesis of triazole- and pyridine-bridged porphyrin–chlorin and porphyrin dimers
✍ Afaf R. Genady; Detlef Gabel πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 114 KB

The synthesis of 4-amino-1,2,4-triazole linked porphyrin-chlorin dimer and porphyrin dimer is described. New cationic porphyrin dimers were synthesized via the alkylation of the nitrogen atoms of 4,4%-bipyridine and 1,2-di-(4-pyridyl)ethene by meso-monobromomethylporphyrin. These cationic bisporphyr